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Understanding Overall Survival
How Progression-Free Survival and Overall Survival Are Different
What Overall Survival Really Means
Improved overall survival is a promising result that some women with HR+, HER2- metastatic breast cancer (mBC) are seeing in clinical trials, so it's important to understand what exactly the term means. Watch the video below to learn about the significance of overall survival (OS) and progression-free survival (PFS)—2 very important terms with very different meanings.
There Is a Difference Between Progression-Free Survival and Overall Survival:
PROGRESSION-FREE SURVIVAL (PFS)
The amount of time cancer doesn’t grow or spread while on treatment. It’s about putting cancer growth on pause.
OTHER WAYS TO DESCRIBE PFS
Amount of time disease progression is delayed
Living longer without your cancer getting worse
More time without disease progression
OVERALL SURVIVAL (OS)
The total time living with metastatic breast cancer. It’s about adding more days to a person’s life.
OTHER WAYS TO DESCRIBE OS
Living longer
More time to live
A chance to live longer
Overall survival is the gold standard in cancer clinical trials. Not all treatments have proven overall survival. KISQALI has—multiple times
