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Chart showing the recommended dosing schedule for KISQALI, NSAI when taken with KISQALI, and Fulvestrant when taken with KISQALI
How to Take KISQALI
KISQALI Is a Convenient Once-Daily Oral Tablet

KISQALI is taken by mouth on a 4-week dosing cycle in combination with either an oral nonsteroidal aromatase inhibitor (NSAI) (eg, letrozole or anastrozole) or fulvestrant, an injection administered by your health care provider.

Recommended Dosing

For the first 3 weeks in a cycle, you’ll take your 3 KISQALI pills once daily. On the fourth week, you won’t take any KISQALI pills. If you’re taking an oral NSAI, on the fourth week, you'll take only that. If you’re receiving fulvestrant, talk to your doctor about your injection schedule.

Chart showing the recommended dosing for KISQALI + hormone therapy. First column showing dosing of KISQALI 600mg (three 200-mg tablets) once daily for 3 weeks, followed by 1 week without taking KISQALI. Second column showing dosing of NSAI when taken with KISQALI. Follow your doctor’s recommended dosing schedule. Third column showing dosing of fulvestrant when taken with KISQALI. 500-mg dose on days 1, 15, and 29 during the first month of treatment, and 500-mg dose once monthly thereafter.
Dosing Instructions
  • Take the recommended dose of KISQALI once each day at about the same time, preferably in the morning

  • You can take KISQALI either with or without food

  • Swallow KISQALI tablets whole with a glass of water. Do not chew, crush, or split the tablets

  • Do not take any KISQALI tablets that are broken, cracked, or that look damaged

  • Avoid grapefruit and grapefruit juice while taking KISQALI

  • If you miss a dose of KISQALI or vomit after taking a dose of KISQALI, do not take another dose on that day. Take your next dose at your regular time

  • If you take too much KISQALI, call your doctor right away or go to the nearest hospital emergency room

Important Safety Information

What is the most important information I should know about KISQALI ?

KISQALI may cause serious side effects, including:

Lung problems. KISQALI may cause severe or life-threatening inflammation of the lungs during treatment that may lead to death. Tell your health care provider right away if you have any new or...


KISQALI is a prescription medicine used to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer that has gotten worse or has spread to other parts of the body (metastatic), in combination with:

  • an aromatase inhibitor as the first endocrine-based therapy; or...