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How KISQALI Works
KISQALI + A NONSTEROIDAL AROMATASE INHIBITOR OR FULVESTRANT
KISQALI is a targeted treatment
KISQALI is not chemotherapy—it's a pill you take that's called a targeted treatment, meaning it blocks, or interferes with, substances that play a role in cancer cell growth. Targeted therapies affect cancer cells, but can also affect healthy cells.
Menopausal status determines the hormone therapy you take with KISQALI because HR+, HER2- metastatic breast cancer (mBC) is fueled by hormones like estrogen
Premenopausal means that you are still producing estrogen from your ovaries, in addition to estrogen that is created in other tissues throughout the body
Premenopausal women are given goserelin and a nonsteroidal aromatase inhibitor (NSAI) along with KISQALI
Postmenopausal means that you are no longer producing estrogen from your ovaries
Postmenopausal women are given an NSAI or fulvestrant along with KISQALI
See How KISQALI Works with an NSAI or Fulvestrant
To understand how KISQALI works with a nonsteroidal aromatase inhibitor (NSAI) (eg, letrozole or anastrozole) or fulvestrant, it's important to learn about the role that hormones/hormone receptors play in causing your type of cancer cells to grow and divide.