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How KISQALI Works

KISQALI + A NONSTEROIDAL AROMATASE INHIBITOR OR FULVESTRANT

KISQALI is a targeted treatment

KISQALI is not chemotherapy—it's a pill you take that's called a targeted treatment, meaning it blocks, or interferes with, substances that play a role in cancer cell growth. Targeted therapies affect cancer cells, but can also affect healthy cells.

Menopausal status determines the hormone therapy you take with KISQALI because HR+, HER2- metastatic breast cancer (mBC) is fueled by hormones like estrogen

Premenopausal means that you are still producing estrogen from your ovaries, in addition to estrogen that is created in other tissues throughout the body

Illustration of woman pointing to ovaries and other tissues of the body that create estrogen. Text says estrogen is still being produced

Premenopausal women are given goserelin and a nonsteroidal aromatase inhibitor (NSAI) along with KISQALI

Illustration of 2 women. On the 1st woman the arrows point to ovaries. Text says goserelin stops the ovaries from the making estrogen. On the 2nd woman arrows point to cells. Text says the NSAI stops the creation of estrogen outside of the ovaries to lower the amount that can bind to cancer cells.

Postmenopausal means that you are no longer producing estrogen from your ovaries

Illustration of woman pointing to ovaries. Text says no longer producing estrogen

Postmenopausal women are given an NSAI or fulvestrant along with KISQALI

Illustration of woman pointing to ovaries and cancer cells. Text says an NSAI or fulvestrant lowers the amount of estrogen that can bind to cancer cells.

See How KISQALI Works with an NSAI or Fulvestrant

To understand how KISQALI works with a nonsteroidal aromatase inhibitor (NSAI) (eg, letrozole or anastrozole) or fulvestrant, it's important to learn about the role that hormones/hormone receptors play in causing your type of cancer cells to grow and divide.

Next: How to Take KISQALI >