KISQALI is a prescription medicine used to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer that has gotten worse or has spread to other parts of the body (metastatic), in combination with:

• an aromatase inhibitor as the first endocrine-based therapy; or

• fulvestrant as the first endocrine-based therapy or following disease progression on endocrine therapy in postmenopausal women or in men.

Click here to learn more about results with KISQALI.

KISQALI is a targeted treatment for HR+ (ER+ and/or PR+), HER2- metastatic breast cancer that blocks, or interferes with, substances that play a key role in cancer cell growth and survival. KISQALI affects cancer cells, but can also affect healthy cells.

Learn how KISQALI and hormone therapy or fulvestrant work together to help delay disease progression.

Combination therapy is a treatment strategy of taking multiple medicines. By combining KISQALI and either a nonsteroidal aromatase inhibitor (NSAI) or fulvestrant, you’ll have 2 medicines working differently, but together, to help slow the growth and spread of your metastatic breast cancer.

Learn how KISQALI and hormone therapy or fulvestrant work together.

See the proven results of KISQALI + hormone therapy or fulvestrant.

Overall survival is about living longer with metastatic breast cancer. Learn how overall survival is different from progression-free survival.

The most common side effects of KISQALI are neutropenia, nausea, infections, fatigue, diarrhea, leukopenia, vomiting, hair loss, headache, constipation, rash, and cough. KISQALI can also cause more serious side effects. Learn more about the potential side effects of KISQALI.

Although not all side effects can be managed, your health care team may offer suggestions to help manage some of the side effects of KISQALI. It’s important to talk with your doctor or nurse about side effects you experience and the best ways to manage them. Get tips about managing some common KISQALI side effects.

KISQALI is a prescription medicine that is a convenient once-daily oral tablet that comes in an easy-to-use blister pack. Your health care provider will prescribe the dose of KISQALI that's right for you. You should take KISQALI exactly as your health care provider tells you. Take KISQALI each day at about the same time, preferably in the morning. Do not change your dose or stop taking KISQALI unless your health care provider tells you. You may take KISQALI with or without food. Ask your doctor about the recommended dose of your nonsteroidal aromatase inhibitor (NSAI) or fulvestrant. Learn more about taking KISQALI.

Avoid eating grapefruit and avoid drinking grapefruit juice. Also avoid taking St. John's wort (Hypericum perforatum) while taking KISQALI.

The KISQALI FEMARA^® (letrozole) Co-Pack is a prescription medicine used as the first hormonal-based therapy to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer that has spread to other parts of the body (metastatic).

The KISQALI FEMARA Co-Pack contains 2 different types of medicines:

• The violet tablet contains the medicine KISQALI.

• The yellow tablet contains the medicine FEMARA.

It is not known if KISQALI or the KISQALI FEMARA Co-Pack are safe and effective in children.

Novartis Pharmaceuticals Corporation is committed to helping make treatment with KISQALI as affordable as possible. Learn about Savings & Support.

Novartis Patient Support is a personalized support program that gives you a dedicated team in your corner. After you've been prescribed KISQALI, either you or your loved one can sign up. Just ask your health care provider, call 1-866-433-8000, or click here for Savings & Support.

Yes. The Novartis Patient Support program is completely free to those who have been prescribed KISQALI.

If you take too much KISQALI, call your doctor right away or go to the nearest hospital emergency room. If you miss a dose of KISQALI or vomit after taking a dose of KISQALI, do not take another dose on that day. Take your next dose at your regular time.