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HR+, HER2- Metastatic Breast Cancer Diagnosis
Receiving a Metastatic Breast Cancer Diagnosis

A metastatic breast cancer diagnosis can be shocking. You may feel scared and overwhelmed. As you process your diagnosis, keep in mind that this is not your fault. Metastatic breast cancer doesn’t discriminate, and it affects thousands of people each year.

Here are some facts to consider:

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    Metastatic breast cancer can develop years after an original diagnosis

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    20% to 30% of people with an early stage diagnosis will experience a metastatic recurrence of their cancer

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    About 6% of people are diagnosed with metastatic breast cancer from the start—this is also known as de novo metastatic

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    Both women and men can be diagnosed with metastatic breast cancer

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    There is no cure for metastatic breast cancer, but it can be treated

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    Metastatic breast cancer treatment is lifelong, and focuses on slowing the growth and spread of tumors—and with some treatments, helping women and men live longer

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    Nearly 80% of young women diagnosed with breast cancer find abnormal changes in their breast themselves

Two Types of Metastatic Breast Cancer Treatment

Metastatic breast cancer treatment can be different than early stage breast cancer treatments. Metastatic breast cancer treatment options can include the use of medicines that slow the growth and spread of tumors, in addition to local therapies, like surgery and radiation therapy.

There are two types of metastatic breast cancer treatment:

Illustration showing how systemic metastatic breast cancer treatment moves through the bloodstream to treat the entire body.


Systemic treatments move through the bloodstream and treat the entire body.

These treatments include:

  • Chemotherapy

  • Hormonal therapy

  • Targeted therapies, like KISQALI. Targeted therapies affect cancer cells, but can also affect healthy cells

Illustration showing how local breast cancer treatments target the tumors.

Local treatments target the tumors. These treatments include:

  • Surgery

  • Radiation therapy

There’s no one right way to treat metastatic breast cancer. If you’ve recently been diagnosed, it’s important to partner with your doctor in order to determine the type of treatment plan that’s right for you.

Important Safety Information

What is the most important information I should know about KISQALI ?

KISQALI may cause serious side effects, including:

Lung problems. KISQALI may cause severe or life-threatening inflammation of the lungs during treatment that may lead to death. Tell your health care provider right away if you have any new or...


KISQALI is a prescription medicine used to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer that has gotten worse or has spread to other parts of the body (metastatic), in combination with:

  • an aromatase inhibitor as the first endocrine-based therapy; or...